Chelsea boss Enzo Maresca makes 10 changes to the side that beat Premier League champions Liverpool 3-1 on Sunday.
Marc Cucurella is the only player to keep his place but the big news is a first start for 16-year-old midfielder Reggie Walsh, who only made his club debut in the first leg a week ago.
Chelsea XI: Jorgensen, Gusto, Adarabioyo, Badiashile, Cucurella, Acheampong, James, Dewsbury-Hall, Walsh, Sancho, George.
Subs: Sanchez, Bergstrom, Colwill, Chalobah, Antwi, Caicedo, Fernandez, Palmer, Madueke, Neto, Mheuka, Jackson.
Jani Honkavaara makes two changes to the Djurgarden side that featured in the first leg in Sweden.
Viktor Bergh and Miro Tenho comes in to the line-up as centre-back Marcus Danielson drops to the bench and right-back Adam Stahl misses out because of an injury.
Djurgarden XI: Rinne, Kosugi, Tenho, Une, Bergh, Finndell, Stensson, Gulliksen, Priske, Haarala, Nguen.
Subs: Croon, Danielson, Alemayehu, Manneh, Selfven, Persson.
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